Hepatocellular carcinoma in tyrosinemia type 1 without clear increase of AFP.
نویسندگان
چکیده
Patients with hereditary tyrosinemia type 1 have an elevated risk of developing hepatocellular carcinoma, especially if initiation of treatment with 2-(2-nitro-4-trifluoro-methylbenzoyl)-1,3-cyclohexanedione is delayed. Hepatocellular carcinoma can usually be suspected when there are increased α1-fetoprotein levels and characteristic imaging features. The present case shows that a lack of a clear increase in α1-fetoprotein should still lead to consideration of liver transplantation when imaging features change.
منابع مشابه
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عنوان ژورنال:
- Pediatrics
دوره 135 3 شماره
صفحات -
تاریخ انتشار 2015